History | Staff | Courses | Research

  Head of the Department:

  Prof. Dr. Stefan Nikolov, D. Sc.
  Tel.: (+359-2)9879874 or (+359-2)9236541

  E-mail: snikolov@pharmfac.acad.bg

Brief historical outline:

The Department was established in 1942 as Department of Pharmacognosy and Galenic Pharmacy following the setting up of the Section of Pharmacy at the Faculty of Natural Science and Mathematics at the University of Sofia. Throughout 1942 the main subject was botany at first read by Prof. N. Arnaudov then by Academician D. Yordanov. In 1943/44 a course in pharmacognosy was introduced read by A. Boichinov, Ph.D. In 1947 the Department of Pharmacognosy was established as a separate unit. Prof. A. Boichinov (1900 - 1967) was one of the founders and the first head of the department. In 1958 botany came under the responsibilities of the Department of Pharmacognosy and the department acquired its present structure. In 1968 the Laboratory of Control and Standardization of Drugs was affiliated to the department.

Heads of the Department since its establishment: Prof. A. Boichinov, Prof. H. Ahtardjiev, Prof. S. Valev, Prof. I. Assenov, and Prof. Dr. St. Nikolov since 1999.

Teaching staff:

		Lecturers: Prof. Dr. Stefan Nikolov (pharmacognosy); Assoc. Prof. Dr. Gerassim Kitanov (pharmacognosy); Assoc. Prof. Dr. Iliana Yonkova (pharmacognosy); Assoc. Prof. Dr. E. Kozhuharova (botany); Assistant professors: Dr. P. Nedialkov, Dr. N. Benbassat, St. Ninov, P. Zdraveva, R. Gevrenova, V. Balabanova.
Prof. G. Kitanov	Prof. I. Yonkova

Specialists with higher education - 1;

Technical staff - 3;

Subjects and duration of Courses:

Core Subjects:

Pharmaceutical Botany IV-V semesters

(Lectures - 60, seminars - 90, practicum - 48);

Pharmacognosy VI - VIII semesters

(Introduction - 10, lectures - 90, seminars - 195, practicum - 48).

Courses offered at:

Undergraduate level (regular and extramural students);

Postgraduate level.

Postgraduate courses in: Medicinal plants and herbals.

Experimental Laboratories:

Anatomy, morphology and classification of plants - 2;

Macroscopic and microscopic identification of drugs - 2;

Phytochemical analysis of drugs - 1;

Main fields of Research:

Phytochemistry (isolation and study of the structure of natural compounds, mainly phenols and saponines);

Standardization (quantitative and qualitative analysis of drugs and pharmaceutical products extracted from medicinal plants);

Study of the dynamics of accumulation of bioactive substances in

medicinal plants;

Chemotaxonomic studies;

In vitro cultures (regulation of biosynthesis of natural products in plant cell and tissue cultures);

Taxonomy, horology and mapping of higher plants;

Marine algae (taxonomic, ecobiological and phytochemical study of

benthic algae);

Basic Methods of Research:

Extraction from plants (total and gradual);

Chromatography-TLC (analytical and preparative), paper, column, HPLC;

Spectroscopy (UV, IR, ¹H and ¹³C-NMR, MS);

Chemical Reactions (hydrolysis, methylation, acetylation, etc.);

Qualitative and quantitative, spectrophotometric, densitometric analysis; liquid chromatography;

Tissue cultivation of medicinal plants;

Microscopy;

Chromosomal analysis of medicinal plants.

Basic Laboratory Equipment:

Specord UV-VIS (Zeiss, Jena); Specol 11 (Zeiss, Jena); Spectrophotometer 1203 (SHIMATZU); Densitometer Scanner 2 (CAMAG); HPLC (VARIAN); Incubator JOAN; Laminar box; Autoclave; Electronic analytical scales for measuring humidity (SARTORIUS).

Medical Orientation of Studies:

Isolation of substances of plant origin in greater quantities for pharmacological testing;

Development of methods of analysis of bioactive substances of plant origin;

Standardization of plant drugs and pharmaceutical products derived from them. 

Last modified: 31.01.2004